Inherited variant of erythrocyte carbonic anhydrase in micronesians from Guam and Saipan.
نویسندگان
چکیده
A variant of one form of red cell carbonic anhydrase was discovered in "Chamorro" inhabitants from the islands of Guam and Saipan. Segregation of this trait in four pedigrees indicates that it is under the control of a single autosomal gene.
منابع مشابه
Characterization of a mutant human erythrocyte carbonic anhydrase: carbonic anhydrase Ic-Guam. The amino acid substitution and carboxylesterase and hydratase activities.
Evidence is presented which indicates that an arginine residue has substituted for a glycine residue in the abnormal human erythrocyte carbonic anhydrase, CA Ic ouam. The ratio of the amount of mutant to normal enzyme isolated from hemolyzates of individuals heterozygous for the variant averaged 0.56:1. No significant differences were observed between the specific carboxylesterase activities or...
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عنوان ژورنال:
- Science
دوره 140 3562 شماره
صفحات -
تاریخ انتشار 1963